Rosiced Cream 0.75% Metronidazole Rosacea Tube 30g,Rosiced Crema 0,75% Metronidazolo Rosacea Tubo, 30g

• Therapeutic indications

Rosiced is used in the topical or treatment of the inflammatory papulopustular manifestations of rosacea.

• Dosage and Posology

The drug should be taken according to the following doses and methods: apply and gently massage a thin layer of cream on the affected skin of the face twice a day, for a usual duration of treatment from 6 to 12 weeks. If necessary, the treatment can be continued. In the absence of clinical improvement, therapy should be discontinued.

There are no adequate clinical data on the efficacy and safety of Rosiced cream in children; therefore Rosiced cream should not be used in children. The areas to be treated must be cleansed before applying the cream. Patients can use non-comedogenic and non-astringent cosmetics after applying the cream.

• Overdose

Overdose is extremely unlikely. The cream should be removed by rinsing with warm water. There are no data on overdose in humans. Acute oral toxicity studies with the topical gel formulation containing 0.75% metronidazole in rats showed no toxic action with doses up to 5g of finished product per kg body weight, the highest dose used. . This dose is equivalent to oral administration of 12 x 30g tubes of 0.75% metronidazole cream for an adult weighing 72 kg and 2 tubes of cream for a child weighing 12 kg.

• Contraindications
• First trimester of pregnancy
• Hypersensitivity to medicines containing metronidazole or other 5-nitroimidazoles. The only exception is cases of life-threatening infections or where other medicines have been found to be ineffective.
• Patients with hypersensitivity to any of the excipients.
• In patients with severe hepatic injury, dyshematopoiesis and central or peripheral nervous system disease, a careful risk / benefit assessment is required prior to treatment.

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